Drugdiscovery >> Publications >> News
5048
Views
Novel biological pathway discovered in triple negative breast cancer - drugdiscovery.com
Novel biological pathway discovered in triple negative breast cancer - drugdiscovery.com


Triple negative breast cancer is an aggressive form of cancer with limited responsiveness to approved therapy and not many treatment options for patients. The discovery of a new pathway and the possibility to modulate it so it leads to inhibition of cancer cell proliferation offers hope for new and effective treatments for breast cancer patients.
Read More >>


Tags: triple negative, breast cancer, discovery, new treatments, biological pathway - August 14, 2013
Related Articles
2734
Views
Potential new therapeutic target in triple negative breast cancer identified Potential new therapeutic target in triple negative breast cancer identified
A discovery of the significance of amino acid cysteine for cancer cell growth in triple-negative breast cancer could lead to new therapeutic approach to this difficult to treat type of cancer. Read More >>

Tags: triple negative, breast cancer, research, cysteine, cysteine transporter, inhibitor

5434
Views
Proteasome inhibitors might be effective in aggressive breast cancer treatment Proteasome inhibitors might be effective in aggressive breast cancer treatment
A research conducted on triple-negative tumor cells in vitro shows that these cells require active proteasomes in order to live. These data suggest that triple-negative breast cancers may respond to t Read More >>

Tags: breast cancer, triple negative, proteasomes, proteasome inhibitor, Velcade

5861
Views
New models of drug-resistant breast cancer offer hope for better treatments New models of drug-resistant breast cancer offer hope for better treatments
Scientists have shown that transplanting human breast tumors into mice creates excellent models of metastatic cancer which could be valuable in the search for more effective treatments. Read More >>

Tags: breast cancer, treatment, better treatment, metastatic cancer model, new model, mice, mouse, tumor transplantation

5472
Views
Potential new target  for cancer therapy discovered Potential new target for cancer therapy discovered
Researchers at Spanish National Cancer Research Center have decoded a new mechanism that regulates cell division, and identified its key molecule, Greatwall, as a potential target for oncology treatme Read More >>

Tags: cell division, new mechanism, Greatwall, potential target, oncology, cancer, treatment, research, discovery

4404
Views
Early breast cancer: shorter radiotherapy might be a better option Early breast cancer: shorter radiotherapy might be a better option
Results from a 10-year UK study show that in patients with early breast cancer, lower overall dose of radiotherapy through fewer, higher doses is at least as effective and safe as the current standard Read More >>

Tags: breast cancer, early, radiotherapy

4042
Views
Predicting substrates of Human Breast Cancer Protein Predicting substrates of Human Breast Cancer Protein
Human breast cancer resistance protein (BCRP) is an ATP-binding cassette (ABC) efflux transporter that confers multidrug resistance in cancers and also plays an important role in the absorption, distr Read More >>

Tags: BCRP, substrates

4749
Views
New light shed on pulmonary hypertension. Hope for a cure? New light shed on pulmonary hypertension. Hope for a cure?
Scientists at the Stanford University School of Medicine have discovered that the disease may be caused by a molecular pathway that promotes inflammation and targeting this pathway could provide a pos Read More >>

Tags: pulmonary hypertension, inflammation, molecular pathway, blood vessel inflamation, research, cure

4386
Views
Potentially promising drug target for treating depression discovered Potentially promising drug target for treating depression discovered
An enzyme called Rines regulates MAO-A, a major brain protein controlling emotion and mood. Further research promises insights into the treatment of diseases associated with emotions such as depressio Read More >>

Tags: Rines, MAO-A, depression , drug target, brain molecule, emotions, mood

3725
Views
A possible antiviral drug path to Herpes discovered A possible antiviral drug path to Herpes discovered
Scientists have made a discovery which enabled them to lock up herpes virus DNA inside its viral carriers reducing viral infectiveness up to ten thousandfold. Read More >>

Tags: herpes, herpesvirus, discovery, capsid, viral DNA, antiviral drug path

3286
Views
New genetic variants associated with multiple sclerosis discovered New genetic variants associated with multiple sclerosis discovered
Scientist have recently identified additional 48 genetic variants influencing the risk of developing multiple sclerosis, providing additional key insights into the biology of this condition and under Read More >>

Tags: MS, multiple sclerosis, genetic variants, alleles, genes, risk, research, genetic

MOST VIEWED
HOME | ABOUT | PRIVACY POLICY | TERMS & CONDITIONS | ADVERTISE | CONTACT
All rights reserved drugdiscovery.com 2013