Drugdiscovery >> Clinical Trials >> News
4673
Views
Clinical trial failures - drugdiscovery.com
Clinical trial failures - drugdiscovery.com


Clinical trial failures can kill biopharma companies. While some larger firms can eventually recuperate from the loss of millions invested in a drug that fails its trials, for many companies it can mean layoffs, buyouts, and even shutdowns—just look at TeGenero, a company that filed for insolvency in 2006 after its disasterous Phase I clinical trial of TGN1412 nearly killed its first human subjects.
Read More >>


Tags: Clinical trial, failure - July 11, 2013
Related Articles
3831
Views
CCL Clinical trial through the eyes of a patient CCL Clinical trial through the eyes of a patient
ABT-199 is a chronic lymphocytic leukemia (CLL) drug at Phase 1. Harley Hudson is taking part in the trial and hopes to get at least a long term solution for his illness. Read More >>

Tags: solution, illness, CLL, chronic lymphocytic leukemia, clinical trial, cancer

8357
Views
Medivir’s bone drug successful in Phase 1 clinical trial Medivir’s bone drug successful in Phase 1 clinical trial
The investigational cathepsin K inhibitor MIV-711, used as the treatment of osteoarthritis and other bone related disorders, has shown to be safe and tolerable at doses where it potently decreased car Read More >>

Tags: Medivir, cathepsin K inhibitor, MIV-711, osteoarthritis, bone, drug, invstigational, clinical trial

6343
Views
Sofosbuvir effective in Phase II clinical trial for  hepatitis C Sofosbuvir effective in Phase II clinical trial for hepatitis C
Gilead's experimental drug sofosbuvir in combination with ribavirin showed to be effective and safe interferon-free therapy for even some of the toughest hepatitis C cases. Read More >>

Tags: sofosbuvir, hepatitis C, interferon-free therapy, ribavirin, clinical trial, Gilead

7541
Views
Special Protocol Assessment  for a Phase 3 clinical trial of antibiotic plazomicin Special Protocol Assessment for a Phase 3 clinical trial of antibiotic plazomicin
Plazomicin is a next-generation aminoglycoside antibiotic engineered by Achaogen. It has potent bactericidal activity against important gram-negative pathogens, including carbapenem-resistant Enteroba Read More >>

Tags: plazomicin, antibiotic, aminoglycoside antibiotic, next generation, Achaogen, gram-negative, CRE, clinical trial, multi-drug resistant, MDR, bacterial infections

7245
Views
A global Phase 3 clinical trial for Alzheimer’s disease to be lounched A global Phase 3 clinical trial for Alzheimer’s disease to be lounched
Takeda and Zinfandel have announced the initiation of TOMMORROW Phase 3 clinical trial which will investigate a genetic-based biomarker risk assignment algorithm for the predicition of the risk of mil Read More >>

Tags: clinical trial, global, Alzheimer’s disease, Takeda, Zinfandel, risk assignment algorithm, cognitive impairment risk, pioglitazone, investigational drug

13838
Views
PAT-SM6 antibody successful in Phase I/IIa clinical trial for multiple myeloma PAT-SM6 antibody successful in Phase I/IIa clinical trial for multiple myeloma
Patrys Limited has released additional clinical data for six end-stage, multi-resistant multiple myeloma patients treated with PAT-SM6. The trial is progressing to its 4th and final patient cohort. Read More >>

Tags: multiple myeloma, clinical trial, PAT-SM6, antibody, Patrys Limited, end stage

5607
Views
Lampalizumab  effective in Phase II clinical trial for macular degeneration Lampalizumab effective in Phase II clinical trial for macular degeneration
Roche’s new drug for age-related macular degeneration, lampalizumab, showed effective in slowing the progression of AMD in patients with advanced disease, shrinking the area of geographic atrophy by Read More >>

Tags: macular degeneration, age related, AMD, lampalizumab, clinical trial, Roche, new treatnment

4373
Views
First Clinical Trial With Induced Pluripotent Stem Cells Grows Closer in Japan First Clinical Trial With Induced Pluripotent Stem Cells Grows Closer in Japan
Researchers at the RIKEN Center for Developmental Biology in Kobe plan to generate replacement retinal pigment epithelial cells from iPS cells generated from patients suffering age-related macular deg Read More >>

Tags: Pluripotent Stem Cells, Clinical trial

8092
Views
Promising results of Reolysin in Phase 2 clinical trial in patients with squamous cell carcinoma of the lung Promising results of Reolysin in Phase 2 clinical trial in patients with squamous cell carcinoma of the lung
Oncolytics Biotech’s drug Reolysin, used in combination with carboplatin and paclitaxel, has shown high tumor shrinkage in patients with metastatic or recurrent squamous cell carcinoma of the lung Read More >>

Tags: Reolysin, clinical trial, squamous cell carcinoma of the lung, SCCLC, Oncolytics Biotech

5727
Views
Edison Pharmaceuticals announces Phase 2 trial of EPI-743 Edison Pharmaceuticals announces Phase 2 trial of EPI-743
A trial is a double-blind, placebo-controlled crossover study of EPI-743 in patients with defined or undefined genetic diagnoses that feature cellular oxidation/reduction or energy production defects. Read More >>

Tags: Edison, clinical trial, EPI-743, disorders of energy utilization, oxidation-reduction

MOST VIEWED
HOME | ABOUT | PRIVACY POLICY | TERMS & CONDITIONS | ADVERTISE | CONTACT
All rights reserved drugdiscovery.com 2013