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What is Abilify used for? - drugdiscovery.com


What is Abilify used for? - drugdiscovery.com

The Reality of Abilify

When people experience psychotic symptoms, their doctor may prescribe a drug called Abilify. This drug has been designed to be an antipsychotic medication. When a person takes Abilify, it will change the actions of chemicals in their brain. It is a medication that has been effective in treating such conditions as bipolar disorder, schizophrenia and more. People have also had success in using Abilify to treat their irritability, mood swings, temper tantrums, as well as autistic disorders in children and more.

Companies Offering Abilify

The FDA has approved Otsuka Pharmaceutical Co., Ltd. and Bristol-Myers Squibb company to distribute the drug Abilify.

Using Abilify

It is important people only use this medication the way it's prescribed by a doctor. The directions on the label must be carefully followed. There may be situations where a doctor will change a person's dosage to make certain they get the best results. When using Abilify, it's important to not take more than the prescribed dosage. It's also important to not take less than the prescribed amount or use it for longer than recommended. A doctor will need to regularly check a person's progress after they start taking Abilify.

Clinical Trial

The FDA approval for Abilify was based on the conclusions of a six-week study. It was a double-blind, randomized and placebo-controlled. It evaluated the performance and safety of the drug with pediatric patients. The patients were between the ages of 13 and 17. Each of them had a primary diagnosis of schizophrenia. The clinical trial was conducted at over a hundred centers and in 13 countries. There were over 300 ethnically diverse study participants. Over 84 percent of participants who started the study completed the entire six weeks. Study participants showed significant improvements using Abilify when compared to the placebo.

Major Drug Interactions

Currently, there are 17 different drugs that have been identified as having a major interaction with Abilify. The challenge is with the 90 different classification of these named drugs. It is essential a person discuss all the medications they are taking with their physician prior to starting Abilify. There is a chance for a major interaction with Abilify from prescription as well as over the counter (OTC) medications. A drug that is dangerous to mix with Abilify is any of it formats is Clozapine. All forms of methenamine, propoxyphene, iohexol and more. When a person taking Abilify has caffeine in any form, it can cause them major issues. A physician who prescribes Abilify will know how to avoid dangerous drug interactions.

Moderate Drug Interactions

People who use Abilify should know there are approximately 1,000 different drugs that have been identified as creating a moderate interaction with it. A qualified physician is responsible for determining the potential interaction between drugs. Hundreds of OTC medications will provide a moderate interaction with Abilify. These include many pain relievers, cold and flu medications and more. The number of prescription drugs that provide a moderate interaction with Abilify is extensive. It involves a wide variety of different drug categories. It is recommended individuals carry something with them to identify they are taking Abilify. There are common emergency room medications that could provide a negative interaction with Abilify.

Side Effects

One of the most common side effects identified with using Abilify is a strong sense of restlessness and a need to be moving. Other side effects include constipation, insomnia, blurred vision and fatigue. These are side effects experienced by approximately five percent of Abilify users. Some serious side effects identified were an increased risk of stroke, stiff muscles, changes in pulse, blood pressure change, confusion and sweating. Some other side effects include increased blood sugar levels and changes in cholesterol. Difficulty swallowing has also been reported. Others have experienced uncontrollable movements from different parts of their body such as face, tongue and more. Some patients have experienced a significant decrease in white blood cells. There are even individuals who have experienced seizures. This is more likely to occur if the person using Abilify has a history of seizures.

Combining Alcohol and Abilify

It is not recommended that an individual taking Abilify drink alcohol. If a person has a rare occasional alcoholic drink while using Abilify, there is a chance it may not cause an adverse reaction. Alcohol has been designated as a depressant. If a person suffering from depression drinks alcohol, it is very possible a their symptoms will become worse. Mixing Abilify and alcohol has also proven to increase side effects. An individual may become more susceptible to the effect of alcohol. Individuals have experienced dizziness, drowsiness as well as difficulty in concentrating. Many people experience severe impairment in judgment and thinking.

Dosage

Bipolar disorder is a mental disorder. It causes a person to experience periods of elevated moods and periods of extreme depression. These individuals make poor thought out decisions and don't consider consequences. The chances of suicide with people suffering bipolar disorder is more than 6 percent during a 20-year period. With Abilify depression bipolar disorder, a physician may start their patient on 5 mg once daily. When the patient's system seems to be responding well to Abilify, a doctor can then increase the dosage. If there are physical issues such as poor liver function, a weakened condition or more, the starting dosage could be lower. The average Abilify depression bipolar disorder patient can take up to 30 mg daily.

By Eszter Hazai, PhD Google+

Tags: abilify,schizophrenia - November 2, 2014


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