Potential-new-strategy-in-anti-tuberculosis-drug-development
Potential new strategy in anti-tuberculosis drug development
Researchers have discovered that β-lactone 7, a small molecule that inhibits the ClpP enzyme in Mycobacterium tuberculosis, may be important in development of new anti-bacterial drugs since bacteria cannot survive when ClpP is inhibited....
Tags: β-lactone 7, Mycobacterium tuberculosis, development, drug, ClpP, inhibition...
September 20, 2013
The-improvement-of-vinblastines-cancer-cell-killing-power
The improvement of vinblastine’s cancer cell-killing power
Scientists have developed a method for making a modified, more potent version of one of the most successful chemotherapy drugs, vinblastine....
Tags: vinblastine, analogue, modification, new method, improved version...
September 19, 2013
Three-gene-biomarker-for-earlier-detection-of-aggressive-prostate-cancer
Three-gene biomarker for earlier detection of aggressive prostate cancer
Researchers have identified three genes that together can accurately predict the outcome of prostate tumors that are slow-growing and appear to be low-risk. This could help physicians to better distinguish patients in need of earlier treatments from those in need of "a...
Tags: prostate cancer, biomarker, agressive, three-gene biomarker...
September 19, 2013
Protecting-brain-cells-from-tamoxifen
Protecting brain cells from tamoxifen
AZD6244, an investigational cancer drug currently in clinical trials, has shown to be effective in protecting one type of neural stem cells in central nervous system from the toxic effect of tamoxifen....
Tags: tamoxifen, toxicity, brain, stem cells, nervous system cells, protection...
September 18, 2013
A-diabetes-drug-liraglutide-might-help-in-treating-Alzheimers
A diabetes drug, liraglutide, might help in treating Alzheimer’s
Liraglutide is used to stimulate insulin production in patients with diabetes. Researchers have discovered that it may also reverse symptoms of late-stage Alzheimer’s disease in mice. A major human clinical trial is on its way....
Tags: liraglutide, diabetes, clinical trial, Alzheimer’s...
September 17, 2013
The-effect-of-schizophrenia-and-the-use-of-anti-psychotic-drugs-on-brain-tissue
The effect of schizophrenia and the use of anti-psychotic drugs on brain tissue
By reviewing progressive data from brain scans, scientists have discovered how schizophrenia and the use of anti-psychotic drugs affect the brain....
Tags: effect, schizophrenia, anti-psychotic drugs, brain tissue...
September 17, 2013
Early-breast-cancer-shorter-radiotherapy-might-be-a-better-option
Early breast cancer: shorter radiotherapy might be a better option
Results from a 10-year UK study show that in patients with early breast cancer, lower overall dose of radiotherapy through fewer, higher doses is at least as effective and safe as the current standard of care....
Tags: breast cancer, early, radiotherapy...
September 20, 2013
A-new-biomarker-for-high-diabetes-risk-discovered
A new biomarker for high diabetes risk discovered
In a 12-year diabetes study, researchers have discovered that high levels of 2-aminoadipic acid (or 2-AAA) are linked to significantly higher risk for diabetes. Higher levels of 2-AAA can be detected years before the disease develops....
Tags: biomarker, diabetes, risk, new biomarker...
September 19, 2013
Lung-cancer-potential-new-marker-for-early-diagnosis-identified
Lung cancer: potential new marker for early diagnosis identified
According to a recent study, a protein called isocitrate dehydrogenase shows potential to be used as an early, noninvasive diagnostic biomarker of non-small cell lung cancers. It also may possibly be a good target for the treatment of NSCLC....
Tags: isocitrate dehydrogenase, marker, new, noninvasive diagnostic biomarker, non-small cell lung cancers ...
September 18, 2013
Making-antidepressants-work-faster
Making antidepressants work faster
Researchers have identified the effect of 2 proteins, CREB and CREM on the pharmacology of an antidepressant in a mouse brain, which brings them a step closer to finding the way to accelerate the therapeutic efficacy of antidepressant treatments. ...
Tags: antidepressants, CREB, CREM, effect, accelerate, mice, mouse brain...
September 17, 2013
Hope-for-a-better-long-lasting-treatment-of-macular-degeneration
Hope for a better, long-lasting treatment of macular degeneration
Tested in a mouse study, a class of drugs known as MDM2 inhibitors has shown promise of a better, more lasting treatment for macular degeneration....
Tags: macular degenration, MDM2 inhibitors, treatment, better treatment, new...
September 17, 2013
Gum-disease-causing-bacteria-and-the-increased-risk-of-rheumatoid-arthritis
Gum disease causing bacteria and the increased risk of rheumatoid arthritis
Researchers have discovered a potential mechanistic link between P. gingivalis periodontal infection and rheumatoid arthritis, explaining the increased prevalence of RA in people with periodontal disease. This could shed new light on the treatment and prevention of RA....
Tags: gum disease, periodontal disease, P. gingivalis, rheumatoid arthritis ...
September 17, 2013
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