New-hope-for-Crohns-disease-patients
New hope for Crohn’s disease patients
A team of scientist at NUI Maynooth has discovered that levels of a protein called Pellino3 are dramatically reduced in Crohn’s disease patients. This protein might provide basis for new diagnostic for Crohn’s and even serve as a target for new treatment drugs....
Tags: Crohn’s disease, Pellino3, new treatment, diagnosis...
August 10, 2013
What-causes-fibromyalgia
What causes fibromyalgia?
According to recent study results, a chronic widespread pain in some Fibromyalgia patients might be connected with a peripheral nerve disease called small-fiber polyneuropathy. This discovery could be the first step towards finding better treatments for this disease....
Tags: fibromyalgia, cause, small-fiber polyneuropathy, treatment...
August 10, 2013
Potentially-promising-drug-target-for-treating-depression-discovered
Potentially promising drug target for treating depression discovered
An enzyme called Rines regulates MAO-A, a major brain protein controlling emotion and mood. Further research promises insights into the treatment of diseases associated with emotions such as depression, anxiety, stress-related disorders and impaired social functions. ...
Tags: Rines, MAO-A, depression , drug target, brain molecule, emotions, mood...
August 8, 2013
Drugs-and-Epigenetics
Drugs and Epigenetics
This review discusses novel experimental strategies to the discovery of epigenetic drug targets based on assays which more closely reflect physiological complexity, as well as recent progress in epigentic drug discovery....
Tags: Epigentics, Drug discovery...
August 4, 2013
Predicting-substrates-of-Human-Breast-Cancer-Protein
Predicting substrates of Human Breast Cancer Protein
Human breast cancer resistance protein (BCRP) is an ATP-binding cassette (ABC) efflux transporter that confers multidrug resistance in cancers and also plays an important role in the absorption, distribution and elimination of drugs. ...
Tags: BCRP, substrates...
July 11, 2013
A-step-closer-to-chromosomal-therapy
A step closer to chromosomal therapy
Scientists have succeeded to silence (switch-off) the extra copy of a chromosome implicated in Down syndrome in human cells in the lab. This process is still at a very early (cellular) stage but offers promise that one day it could lead to new medical treatments for thi...
Tags: chromosomal therapy, Down syndrome, chromosomal silencing...
August 10, 2013
Raising-RNA-treatment-potency
Raising RNA treatment potency
Drug candidates that target RNA might gain greater therapeutic potential thanks to small molecules that bind to a disease-causing RNA targets. One such molecule, 2H-4-CA, has been successfully used to bind to disease causing RNA sequence involved in myotonic dystrophy...
Tags: RNA targeting, treatment, myotonic dystrophy type 1, 2H-4-CA...
August 9, 2013
More-effective-prediction-of-lung-cancer-recurrence
More effective prediction of lung cancer recurrence
The results of retrospective study show significantly increased recurrence among patients who had a tumor resection if 5% or more of the cancer had micro-papillary morphology. This findings might help guide surgical decisions in the future....
Tags: lung cancer, recurrence, resection, micro-papillary morphology, lobectomy, ...
August 8, 2013
Evaluation-of-drughuman-serum-albumin-binding-interactions
Evaluation of drug–human serum albumin binding interactions
Human serum albumin is the most abundant plasma protein with an extraordinary binding capacity for both endogenous and exogenous substances. A model was developed that efficiently predicts albumin binding....
Tags: Human Serum Albumin, Binding Interactions...
July 15, 2013
MOST VIEWED
First «« Prev 8 9 10 11 12 Next »»  Last

HOME | ABOUT | PRIVACY POLICY | TERMS & CONDITIONS | ADVERTISE | CONTACT
All rights reserved drugdiscovery.com 2013