Special-Protocol-Assessment-for-a-Phase-3-clinical-trial-of-antibiotic-plazomicin
Special Protocol Assessment for a Phase 3 clinical trial of antibiotic plazomicin
Plazomicin is a next-generation aminoglycoside antibiotic engineered by Achaogen. It has potent bactericidal activity against important gram-negative pathogens, including carbapenem-resistant Enterobacteriaceae. ...
Tags: plazomicin, antibiotic, aminoglycoside antibiotic, next generation, Achaogen, gram-negative, CRE, clinical trial, multi-drug resistant, MDR, bacterial infections...
September 28, 2013
The-results-of-linagliptin-safety-trials-in-patients-with-type-2-diabetes
The results of linagliptin safety trials in patients with type 2 diabetes
Eli Lilly and Boehringer Ingelheim presented the results from two pooled analyses of data from placebo-controlled clinical trials, which examined the safety of the linagliptin in adults with type 2 diabetes, showing that linagliptin is a treatment option for a wide ran...
Tags: lingliptin, type 2 diabetes, safety, clinical trials, Eli Lilly...
September 26, 2013
Merck-continues-the-clinical-development-of-tecemotide-for-lung-cancer
Merck continues the clinical development of tecemotide for lung cancer
Tecemotide (also known as L-BLP25), an investigational MUC1 antigen-specific cancer immunotherapy will be tested in a new Phase 3 trial called START for patients with unresectable, locally advanced Stage 3 non-small cell lung cancer (NSCLC)....
Tags: Merck, tecemotide, lung cancer, non-small cell lung cancer, immunotherapy ...
September 26, 2013
BMS-diabetes-drug-successful-in-late-stage-study
BMS diabetes drug successful in late-stage study
Bristol-Myers Squibb has announced that its diabetes drug dapagliflozin, helped improve blood sugar levels and reduce body weight in patients with type 2 diabetes who were taking a combination of metformin plus sulfonylurea....
Tags: type 2 diabetes, Bristol-Myers Squibb, dapagliflozin, clinical trial, Forxiga...
September 25, 2013
GSKs-Duchenne-muscular-dystrophy-failed-in-late-stage-trial
GSK’s Duchenne muscular dystrophy failed in late-stage trial
A potential treatment for Duchenne muscular dystrophy, drisapersen, did not meet the study's main goal of generating a statistically significant improvement in a six-minute walking distance test compared to the placebo....
Tags: Duchenne muscular dystrophy, drisapersen, new treatment, clinical trial...
September 22, 2013
Smoking-cessation-depression-and-Chantix
Smoking cessation, depression and Chantix
The results of a clinical trial, sponsored by Pfizer, show that varenicline (Chantix), its drug for smoking cessation helps patients with depression quit smoking, without worsening their depressive symptoms.”...
Tags: chantix, varenicline, depression, smoking cesation, smoking...
September 20, 2013
Lillys-cancer-drug-unsuccessful-in-breast-cancer-trial-but-shows-promise-in-gastric-cancer-treatment
Lilly’s cancer drug unsuccessful in breast cancer trial but shows promise in gastric cancer treatment
Eli Lilly’s investigational drug ramucirumab, missed its main goal in a late-stage study in patients with advanced breast cancer. The drug performed better in a separate study in patients with advanced gastric cancer....
Tags: Eli Lilly, Lilly, investigational drug, clinical trials, ramucirumab, breast cancer, gastric cancer...
September 27, 2013
Tresiba-efficient-in-type-2-diabetes-patients-study-shows
Tresiba efficient in type 2 diabetes patients - study shows
The results of the study demonstrate that Novo Nordisk’s recently launched drug Tresiba (insulin degludec) enables patients with type 2 diabetes to sustain good long-term glycemic control, when used with metformin....
Tags: Tresiba, glycemic control, type 2 diabetes, Novo Nordisk, insulin degludec...
September 26, 2013
Edison-Pharmaceuticals-announces-Phase-2-trial-of-EPI-743
Edison Pharmaceuticals announces Phase 2 trial of EPI-743
A trial is a double-blind, placebo-controlled crossover study of EPI-743 in patients with defined or undefined genetic diagnoses that feature cellular oxidation/reduction or energy production defects. ...
Tags: Edison, clinical trial, EPI-743, disorders of energy utilization, oxidation-reduction...
September 25, 2013
Psoriasis-Drug-Tested-Against-Diabetes
Psoriasis Drug Tested Against Diabetes
Encouraging results from the T1DAL study (Targeting effector memory T-cells with alefacept in new onset type 1 diabetes), led by Mark Rigby from Indiana University and Riley Hospital for Children in Indianapolis and sponsored by the Immune Tolerance Network (ITN) with a...
Tags: alefacept, diabetes, psoriasis, treatment, clinical trial...
September 23, 2013
Ovarian-cancer-drug-demcizumab-enters-Phase-2
Ovarian cancer drug demcizumab enters Phase 2
OncoMed Pharmaceuticals’ stem cell product candidate, demcizumab (OMP-21M18) has entered Phase 1b/2 clinical trial and will be tested in combination with paclitaxel in patients with platinum-resistant ovarian cancer, Fallopian tube cancer or primary peritoneal cancer....
Tags: OncoMed, oncomed, demcizumab, ovarian cancer, fallopian tube cancer, primary peritoneal cancer ...
September 20, 2013
Prevention-of-Alzheimers-the-first-clinical-trial-begins
Prevention of Alzheimer’s: the first clinical trial begins
The first clinical trial, which will test whether giving new drug treatments before dementia can prevent Alzheimer’s, has been launched....
Tags: Alzheimer’s, prevention, clinical trial...
September 20, 2013
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