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Injectable-ultrasound-triggered-depot-system-for-on-demand-anticancer-drug-delivery
Injectable, ultrasound-triggered depot system for on-demand anticancer drug delivery
In human medicine, ultrasound is commonly employed both for diagnostic and therapeutic purposes. Ultrasonic guided drug and gene delivery from nanocarriers is a non-invasive, emerging method with many advantages and tremendous potential applications. Among a variety of ...
Tags: alginate, mitoxantrone, on-demand drug delivery, ultrasound-stimulus...
September 15, 2014
Unlocking-anticancer-potential-of-marketed-drugs-collection-of-in-vitroin-vivo-laboratory-and-clinical-data-updated-regularly
Unlocking anticancer potential of marketed drugs: collection of in vitro/in vivo laboratory and clinical data (updated regularly)
There are over 11,500 drugs licensed by the FDA and its foreign counterparts for treatment of human diseases. Screening of these agents for additional pharmacological activities may result in new therapeutic indications for existing drugs representing an innovative rout...
Tags: cancer, clinical trial, drug repositioning, drug repurposing...
August 27, 2014
Quiz-Fat-like-fat-dislike-Structure-related-lipophilicity-differences-of-statins
Quiz: Fat: like, fat: dislike - Structure related lipophilicity differences of statins
Statins are among the most widely prescribed drugs to control cardiovascular events in patients with pathologically elevated cholesterol level. Simvastatin and lovastatin were the first agents approved for clinical use in the 1980s. Statins competitively inhibit HMG-CoA...
Tags: HMG-CoA reductase inhibitor, lipophilicity, lovastatin, mevastatin, pravastatin, simvastatin...
August 23, 2014
Global-Antifungal-Therapeutics-MarketTrends-and-Opportunities-2014-2019
Global Antifungal Therapeutics Market:Trends and Opportunities (2014-2019)
The report titled Global Antifungal Therapeutics Market: Trends and Opportunities (2014-2019) provides an in-depth analysis of global antifungal therapeutics market with focus on antifungal drug classes – Polyenes, Azoles, Echinocandins and Allylamines....
Tags: global antifungal therapeutics market, antifungal therapeutics market, global antifungal therapeutics industry...
August 20, 2014
Quiz-In-recognition-of-drug-chirality
Quiz: In recognition of drug chirality
Sulfinpyrazone is used to treat gout since decreases the serum uric acid level by increasing renal excretion. It is a chiral molecule and belongs to the pyrazolidine class of drug compounds.

Find the asymmetric center in the sulfinpyrazone molecule.

By...

Tags: asymmetric center, chirality, sulfinpyrazone...
August 12, 2014
Quiz-DNA-binding-of-flavonoids
Quiz: DNA binding of flavonoids
Several reports demonstrated the ability of plant derived dietary flavonoids to interact with nucleic acids. For instance, the typical flavonoid agent quercetin was found to be a DNA intercalator.

However, taxifolin, the close congener of quercetin exh...

Tags: DNA binding, flavonoids, intercalation, quercetin, taxifolin...
August 10, 2014
Unfriendly-frequencies-mobile-phone-base-stations-should-kept-at-a-distance
Unfriendly frequencies: mobile phone base stations should kept at a distance
The potential hazardous effects of the radiofrequency (RF) and microwave (MW) radiation on the human health is an evergreen debate over several decades. The rapid development of cell phone systems has associated with emerging concerns about possible health risks of expo...
Tags: brain cancer, cell phone, electromagnetic field, health effects, leukemia, microwave radiation, mobile phone base station, emf...
September 11, 2014
Quiz-Looking-for-chiral-centers-find-them-all
Quiz: Looking for chiral centers: find them all
Fosinopril is a phosphoryl-containing angiotensin converting enzyme (ACE) inhibitor used to treat high blood pressure. It prevents the conversion of angiotensin I to angiotensin II by blocking the enzyme. As an orally active ester prodrug, it is converted in the body to...
Tags: ACE inhibitor, chirality, fosinopril...
August 23, 2014
Experimental-treatments-for-Ebola-disease
Experimental treatments for Ebola disease
Ebola virus, along with its close relative the Marburg virus, makes up the family of negative stranded, RNA viruses known as Filoviridae (filamentous viruses). These extremely lethal, emerging pathogens cause a severe hemorrhagic fever in humans and non-human primates, ...
Tags: antisense, antiviral drugs, chloroquine, Ebola virus, experimental therapy, favipiravir, hemorrhagic fever, small interfering RNA...
August 20, 2014
Global-Breast-Cancer-Market-Report-2014-Edition-New-Report-by-Koncept-Analytics
Global Breast Cancer Market Report: 2014 Edition – New Report by Koncept Analytics
Breast cancer is the most frequently diagnosed cancer and the leading cause of cancer death in women. Breast cancer knows no boundaries be it age, gender, socioeconomic status or geographic location....
Tags: breast cancer market report, global breast cancer market...
August 13, 2014
A-novel-indication-of-cholesterol-lowering-drugs-strengthen-your-bones-by-statins
A novel indication of cholesterol-lowering drugs: strengthen your bones by statins
Statins are a class of commonly prescribed drugs that are the cornerstone of lipid-lowering therapy through the inhibition of hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase enzyme. During hepatic cholesterol biosynthesis, these agents block competitively the c...
Tags: bone formation, bone fracture, lovastatin, osteoporosis, simvastatin, statins...
August 11, 2014
Globin-hunter-globulin
Globin hunter globulin
Preeclampsia (PE) is one of the most common complications of pregnancy. As a multi-system disorder, PE is still one of the dominating causes of maternal morbidity and mortality being responsible for 50,000-60,000 deaths/year worldwide. It may appear from 20 weeks of...
Tags: alpha1-microglobulin, endothelial damage, fetal hemoglobin, oxidative stress, pre-eclampsia...
August 8, 2014
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